Effect of organic (with Humidol Standard) and mineral (with NPK) fertilisation on some physico-chemical and chemical properties of sandy soils in the LGOM region were studied. The experiment was founded with two factors and a sub-block method. Humidol Standard was introduced once, and mineral fertilisation each year. The studies showed that fertilisation with Humidol Standards increased the amount of organic matter, improved fraction composition of humic compounds and physico-chemical properties of sandy soils. Fertilisation with Humidol Standard combined with NPK can be a safe agrotechnical treatment that improves soil fertility in a short period of time in the region of LGOM.