The aim of the research was to define the influence of treatment methods, with the use of growth biostimulators and herbicide on the yield structure of three varieties of edible potato. The series of field research was carried out in the years 2015-2017, in the region of eastern Poland, in Biała Podlaska municipality, in Lubelskie voivodship, on light, acidic soil. The experiment was constructed with the use of random sub-blocks method in three repetitions. The tested factors included: I. factor – three early edible potato varieties Owacja, Bellarosa, Vineta; II. factor – five methods of treatment of the field of potato crops with the use of growth biostimulators: GreenOk-Uniwersal Pro and Asahi SL and their combinations with Avatar 293 ZC herbicide. As a result of the conducted research it was found that the methods of treatment with the use of growth biostimulators and herbicide had a positive effect on the structure of potato tuber yields, compared to the standard object on which only mechanical care was applied. The highest weight percent of large tubers input (in fractions >51mm) was observed in case of experimental object 4. (in case of which herbicide Avatar 293 ZC and GreenOK Universal-PRO preparation were applied) as well as experimental object 3 (post applying biostimulator Asahi SL). Varieties cultivated in the experiment had a significant impact also on the structure of potato crops. An impact of weather conditions on the structure of potato tubers was further noted. Based on the conducted experiment, it can be concluded that the growth biostimulators, as well as their combination with herbicide, positively influenced the quality parameters of potato tubers. Therefore, these preparations should find wider application in agricultural practice.